Objective To retrieve,appraise and summarize the best evidence of medication management in patients with swallowing disorders. Methods Using the method of evidence-based nursing for swallowing disorders patients,the problem of standard management of taking medicine was put forward. Evidence-based nursing methods were used to search UpToDate,BMJ,JBI,Cochrane Library,Ontario Registered Nurses Association of Canada,British National Institute of Clinical Medicine Guide Library,Scottish Intercollegiate Guidelines Network,National Guideline Clearinghouse,Guidelines International Network,Canadian Medical Association,American Heart Association/American Stroke Association,PubMed,CINAHL,UK NEWT website,Chinese Biology Medical literature database,Yimaitong,China Knowledge Network and other databases including all relevant documents from the date of database establishment to January 2021,covering clinical recommended practice,guideline,evidence summary,systems evaluation,expert consensus. The retrieved literature was evaluated by 3 researchers,and the literature that met the quality standards was extracted for evidence. Results A total of 12 pieces of literature were included,including 2 clinical decisions,2 guidelines,6 evidence summaries,and 2 expert consensused. The best evidence was summarized in 8 areas,including education and training of health care personnel,pre-medication screening and evaluation,multidisciplinary collaboration,compensatory methods,selection of oral solid dosage forms,administration of crushing drugs,gastrointestinal nutrition tube administration,and monitoring and recording of medication effects. Conclusion This study summarized the evidence of the normative management of medication for patients with swallowing disorders,so as to provide evidence-based bases for medical institutions to establish the practice standard of medication procedures for patients with swallowing disorders,and to ensure the safety of medication for patients.